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Quantification of liver microcirculation using X-ray microtomography of vascular corrosion casts

Citace: KRÁLÍČKOVÁ, A., EBERLOVÁ, L., KALUSOVÁ, K., GREGOR, T., KOCHOVÁ, P., LIŠKA, V., KRÁLÍČKOVÁ, M., TONAR, Z. Quantification of liver microcirculation using X-ray microtomography of vascular corrosion casts. In Key Engineering Materials. Durnten-Zurich: Trans Tech Publications Ltd, 2014. s. 505-508. ISBN: 978-3-03785-934-6 , ISSN: 1013-9826
Druh: STAŤ VE SBORNÍKU
Jazyk publikace: eng
Anglický název: Quantification of liver microcirculation using X-ray microtomography of vascular corrosion casts
Rok vydání: 2014
Místo konání: Durnten-Zurich
Název zdroje: Trans Tech Publications Ltd
Autoři: Anna Králíčková , Lada Eberlová , Kristýna Kalusová , Ing. Tomáš Gregor PhD. , Ing. Petra Kochová Ph.D. , Václav Liška , Milena Králíčková , Doc. MUDr. et Mgr. Zbyněk Tonar Ph.D. ,
Abstrakt EN: We used corrosion casts and micro-CT for quantitative description of microvascular network in porcine liver. Using stereological methods, manual tracing of microvessels and analysis of orientation in 3D, we quantified the volume fraction, the surface density, the numerical density, the length density and the tortuosity of microvessels in series of images with 1.875 ?m pixel resolution. Biodur E 20 resin was more suitable forpreparing and quantifying microvascular tree corrosion casts when compared to Mercox II resin. Quantified data could be applicable for correlating 3D models with 2D liver histopathology, for enhancing the interpretation of routine medical CT and for providing data for computer models of tissue perfusion and angiogenesis.
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